The one case of female-to-male transmission was unique in that the couple reported numerous unprotected sexual contacts and noted several instances of vaginal and penile bleeding during intercourse. The odds of male-to-female transmission were significantly greater than female-to-male transmission. The risk of a female assigned at birth transmitting HIV to a male assigned at birth as a result of insertive penile-vaginal intercourse is 4 per 10,000 exposures. Male index cases were more likely to be symptomatic than female index cases. All couples were sampled in the same way. We observed one probable instance (1%) of female-to-male transmission compared with 20% transmission rates in the female partners of infected men. HIV serostatus in the exposed sexual partner. Most partners did not know their serostatus at entry into the study. The majority of couples were monogamous since 1978, white, and in their 30s. The infected index case had a well-established source of risk couples were eliminated if the direction of transmission could not be established. Mouth ulcers or small wounds in the mouth do not pose a risk for HIV transmission. Data from 379 couples at entry to the study are reported: 72 male partners of infected women and 307 female partners of infected men. Participants were recruited from various HIV counseling and testing sites throughout California but were generally interviewed and tested in their homes. 04 chance per sex act of a man acquiring HIV. Survey of infected individuals and their heterosexual partners recruited since 1985. CDC Response: Demographic and other information is obtained on persons reported with AIDS for surveillance purposes. In general, according to this meta-analysis of studies (Heterosexual risk of HIV-1 infection ), there is a. To examine rates of heterosexual transmission of human immunodeficiency virus (HIV) and associated risk factors and to determine the relative efficiency of female-to-male and male-to-female transmission. RESULTS-Overall, 19 (12) male partners and 82 (20) female partners were infected with HIV, suggesting that male to female transmission is 1.9 (95 confidence.
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